Limitations of Efficacy Research
The Definition and Efficacy of Efficacy Research
The American Recovery and Reinvestment Act is law and it contains $1.1 billion in support of comparative effectiveness research (CER), which the Institute of Medicine's Committee on Comparative Effectiveness Research Prioritization has defined as:
…the generation and synthesis of evidence that compares the benefits and harms of alternative methods to prevent, diagnose, treat and monitor a clinical condition, or to improve the delivery of care. The purpose of CER is to assist consumers, clinicians, purchasers, and policy makers to make informed decisions that will improve health care at both the individual and population levels.
"Comparative effectiveness research" and Kindred Delusions," for a good review of the limitations of efficacy research.

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